NOFO Meaning: Notice of Funding Opportunity
Quick Answer: A NOFO, or Notice of Funding Opportunity, is the public announcement for a federal financial-assistance opportunity. This guide is for applicants screening a route.
In this guide (13 sections)
- NOFO Definition: The Official Federal Grant Announcement
- Why OMB Standardized the NOFO Term
- The 8 Required NOFO Sections
- NOFO vs. FOA vs. RFP vs. RFA: A Terminology Guide
- How to Read a NOFO: A Section-by-Section Strategy
- 5 Common Mistakes When Reading a NOFO
- Where to Find NOFOs
- NOFO Timelines: What to Expect
- What to Do After You Find a NOFO
- What the NOFO Doesn't Tell You: Turn It Into a Go-or-Skip Decision
- Related Application Checks
- FAQ: Common Questions
- Sources
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Full answer: A NOFO, or Notice of Funding Opportunity, is the public announcement for a federal financial-assistance opportunity. This guide is for applicants screening a route. Check eight required sections: basic information, eligibility, program description, application contents, submission requirements, review information, award notices, and post-award requirements.
Data note: The required headings and notice-summary rules in this guide were checked against the current electronic Code of Federal Regulations on July 25, 2026. The current NOFO controls its own eligibility, dates, submission method, and award terms.
What Is a NOFO? Notice of Funding Opportunity Explained (2026)
A NOFO is the single most important document you'll read during any federal grant application. It's the rulebook, the scoring guide, and the eligibility checklist all in one. If you don't read the NOFO carefully, you're writing your proposal blind.
This guide explains what a NOFO is, how to read one section by section, how NOFO relates to older terms like FOA and RFP, and the specific mistakes that cause otherwise strong applicants to lose points or get disqualified.
Last updated: July 2026
NOFO Definition: The Official Federal Grant Announcement
A Notice of Funding Opportunity (NOFO) is a public announcement of the availability of federal financial assistance. It gives applicants the information needed to decide whether to apply, including eligibility, program purpose, required application contents, review rules, and submission instructions.
The regulatory basis is 2 CFR 200.204. For openly competed federal assistance opportunities, it requires agencies to announce the opportunity and display required summary information on Grants.gov. The full NOFO must include the Appendix I information.
Length and format vary, but Appendix I requires a table of contents using the same or similar headings. That common structure lets applicants find comparable information across agencies.
Why OMB Standardized the NOFO Term
Before 2024, every agency had its own name for essentially the same document. NIH called them FOAs (Funding Opportunity Announcements). NSF used Program Solicitations. USDA's NIFA used RFAs (Requests for Applications). HUD and DOL used NOFAs (Notices of Funding Availability). Some agencies used multiple terms simultaneously.
This was confusing. An applicant moving from an NIH grant to an ED grant would encounter a completely different naming system for documents that served the same purpose.
In the April 2024 revision to 2 CFR Part 200, OMB standardized the term to NOFO across all federal agencies, effective for awards issued on or after October 1, 2024. The revision also overhauled the NOFO template in Appendix I to Part 200, requiring plain language, a consistent structure, and improved readability.
Agencies are still transitioning. As of early 2026, you'll still see NIH using "NOFO" with legacy FOA numbering formats (like PAR-25-XXX). NIFA formally announced the switch from RFA to NOFO. Some smaller agencies haven't updated all their templates yet.
The practical impact: if you see FOA, NOFA, RFA, or NOFO on a federal agency website, they all refer to the same type of document. NOFO is now the official term.
The 8 Required NOFO Sections
Appendix I requires these eight headings: Basic Information, Eligibility, Program Description, Application Contents and Format, Submission Requirements and Deadlines, Application Review Information, Award Notices, and Post-Award Requirements and Administration. A NOFO may also include an optional Other Information section. Some agency notices retain familiar letter labels, so use the subject matter rather than assuming a letter alone controls.
Basic Information and Program Description
This section explains the purpose of the funding, the policy objectives the agency is trying to achieve, and the activities it will and won't fund. Read this first. If your project doesn't align with the program description, nothing else in the application matters.
Look specifically for: priority areas, populations of focus, geographic restrictions, and any statutory authority cited. The statutory authority tells you whether this is a one-time appropriation or an ongoing program, which affects your chances of getting funded in future cycles.
Eligibility
This section defines who can apply. It covers:
- Eligible applicant types: nonprofits, state governments, tribal organizations, institutions of higher education, for-profits (rare for grants), individuals (very rare)
- Cost sharing requirements: whether matching funds are required and at what ratio
- Threshold eligibility criteria: hard requirements that will disqualify you if unmet (e.g., must serve a specific population, must be located in a designated area)
Don't assume eligibility. Read this section word by word. A common mistake is reading "nonprofit organizations" and assuming that includes all 501(c)(3)s, when the NOFO may further restrict to nonprofits with specific accreditations or operational history.
Application Contents and Format
This section identifies the required forms, narrative components, page limits, formatting rules, file requirements, and any letters or third-party documents. It also identifies information that is required after selection but before an award. Use it to build a compliance checklist before drafting.
Submission Requirements and Deadlines
This is the logistics section. It covers:
- Required forms (SF-424, SF-424A budget form, project narrative, etc.)
- Page limits, font size, and margin requirements
- Submission deadline (date and time, always Eastern Time on Grants.gov)
- Whether a Letter of Intent is required or optional
- How to submit (Grants.gov Workspace, agency-specific portal, or both)
- Required registrations (SAM.gov, Grants.gov AOR status)
The formatting requirements aren't suggestions. If a NOFO says 12-point Times New Roman with 1-inch margins and a 25-page limit, submitting 26 pages in 11-point Arial will get your application rejected. Reviewers are instructed not to read past the page limit.
For detailed guidance on the submission process, see our Grants.gov application guide.
Application Review Information
This is arguably the most strategically important section. It lists the specific criteria that peer reviewers will use to score your application and the point values for each criterion.
A typical scoring breakdown looks like:
- Need for the Project: 20 points
- Quality of Project Design: 30 points
- Quality of Management Plan: 20 points
- Adequacy of Resources: 15 points
- Quality of Evaluation Plan: 15 points
Write your proposal to match these weights. If "Quality of Project Design" is worth 30 points and "Need for the Project" is worth 20, spend proportionally more time on your project design narrative.
This section also describes the review process: whether there's peer review, who the reviewers are (external experts vs. agency staff), and whether there's a second tier of review by agency leadership.
Award Notices and Post-Award Requirements
This section covers what happens after you win: reporting requirements, award conditions, and compliance obligations. While it's less relevant during the writing process, skim it before submitting. It tells you:
- Frequency and type of required reports (quarterly financial, annual progress, final)
- Specific award conditions (data sharing requirements, publication policies)
- Administrative and national policy requirements
Understanding these requirements upfront helps you build a realistic management plan in your proposal. For a deeper look at post-award obligations, read our federal grant compliance requirements guide.
Agency Contacts and Other Information
Names, email addresses, and phone numbers for program contacts and grants management contacts. Note that these are often different people. Program contacts answer questions about the substance of the funding opportunity. Grants management contacts answer questions about forms, submission mechanics, and budget rules.
Always contact the program officer with substantive questions before writing your proposal. They can tell you whether your project idea is a fit. This isn't an unfair advantage. It's expected and encouraged.
The current Appendix I allows an optional Other Information section for related programs, useful agency websites, and routine notices. Review incorporated links, templates, and standard terms because a NOFO may reference them rather than reproduce them.
NOFO vs. FOA vs. RFP vs. RFA: A Terminology Guide
The shift to NOFO has created a terminology maze, especially during the transition period. Here's a clear breakdown.
NOFO (Notice of Funding Opportunity) is the current standard term established by OMB for all federal grant and cooperative agreement announcements. This is what you should use and look for going forward.
FOA (Funding Opportunity Announcement) was NIH's term before the NOFO transition. NIH adopted NOFO in 2024 but retains its legacy numbering formats (PA, PAR, RFA prefixes). If you're searching NIH opportunities, you'll still see FOA used in older guidance documents.
RFP (Request for Proposals) technically refers to contract solicitations, not grants. When a federal agency issues an RFP, it's usually buying a specific service or product through a procurement contract governed by the Federal Acquisition Regulation (FAR), not 2 CFR 200. However, state and local governments and private foundations frequently use RFP for their grant competitions, which creates confusion.
RFA (Request for Applications) was used by NSF, USDA NIFA, and some other agencies. NIFA formally transitioned to NOFO. NSF has been aligning its terminology with the NOFO standard, though the agency deferred publication of the planned NSF 26-1 PAPPG and is issuing supplemental policy notices in the interim.
NOFA (Notice of Funding Availability) was the preferred term at HUD, DOL, and some other agencies. Functionally identical to NOFO.
SGA (Solicitation for Grant Applications) was used by the Department of Labor. Now replaced by NOFO.
The key distinction is between NOFOs (grants/cooperative agreements) and RFPs (contracts). If you see NOFO, FOA, RFA, NOFA, or SGA, they're all the same type of document for grants. If you see RFP, you may be looking at a contract opportunity with different rules.
For definitions of all these acronyms and more, check our grant writing glossary.
How to Read a NOFO: A Section-by-Section Strategy
Reading a NOFO cover to cover on the first pass is inefficient. Here's the approach that experienced grant writers use.
Pass 1: Eligibility Screen (10 Minutes)
Go directly to Section C (Eligibility Information). Read every eligibility criterion. If your organization doesn't meet even one threshold requirement, stop. No amount of excellent writing will overcome an eligibility disqualification.
Check for:
- Organization type restrictions
- Geographic restrictions
- Required partnerships or MOUs
- Cost sharing or matching requirements
- Prior experience requirements
- Registration requirements (SAM.gov, Grants.gov, DUNS/UEI)
Pass 2: Strategic Fit (20 Minutes)
Read Section A (Program Description) and Section E (Review Criteria). These two sections together tell you what the agency wants and how it will measure whether you're delivering it.
Ask yourself: Does my organization's mission and current work genuinely align with what this NOFO is funding? Could I write a strong narrative for each review criterion based on work we're already doing or have concrete plans to do?
If the answer is no, this may not be your competition. Applying for a poorly matched NOFO wastes months of staff time and has a near-zero chance of success.
Pass 3: Feasibility Check (15 Minutes)
Read Section B (Award Information) and the cost sharing requirements in Section C. Can you execute the project within the award ceiling? If the maximum award is $300,000 per year and your project realistically needs $500,000, you'll either need to scale down or find co-funding.
Check whether cost sharing is mandatory. If the NOFO requires a 1:1 match on a $500,000 award, your organization needs to commit $500,000 in cash or in-kind contributions. That's a significant financial commitment.
Pass 4: Full Read (2-3 Hours)
Now read the entire NOFO, start to finish, with a highlighter (physical or digital). Mark every requirement, every "must," every "should," and every reference to a specific form or format. Build a compliance checklist as you go.
Pay special attention to:
- Page limits and formatting rules (Section D)
- Required attachments and supplementary documents
- Whether Letters of Intent are required, optional, or not applicable
- Specific certifications or assurances you'll need to submit
- Deadlines for questions, LOIs, and the full application
Pass 5: Scoring Map (30 Minutes)
Return to Section E and create a scoring map: list each criterion with its point value, then list the sub-criteria under each. This becomes your proposal outline. Every section of your narrative should correspond directly to a scoring criterion.
If a criterion says "The extent to which the applicant demonstrates a clear understanding of the need for the proposed project," your narrative needs a section that explicitly demonstrates your understanding of the need, with data, citations, and local context.
5 Common Mistakes When Reading a NOFO
1. Skimming the Eligibility Section
Organizations can spend months writing a proposal only to discover at submission that they needed a specific state certification they didn't have, or that the NOFO required a partnership with a federally recognized tribal entity. Read every word of Section C before writing a single sentence.
2. Ignoring the Review Criteria Weights
If "Quality of Evaluation Plan" is worth 15 points and you write two paragraphs about evaluation, you're leaving points on the table. Allocate narrative space proportionally to point values. Some applicants allocate page count directly: if evaluation is 15% of the score and you have 25 pages, give evaluation about 4 pages.
3. Missing "Absolute" vs. "Competitive Preference" Priorities
Many Department of Education NOFOs distinguish between absolute priorities (you must address one to be eligible) and competitive preference priorities (you get bonus points if you address them, but they're optional). Missing a competitive preference priority doesn't disqualify you, but ignoring one worth 5 bonus points when your competition addresses it puts you at a real disadvantage.
4. Using Last Year's NOFO
Agencies update NOFOs annually. A NOFO for the same program in FY 2025 and FY 2026 may have different review criteria, different page limits, different eligibility requirements, and a different total funding amount. Always download the current year's NOFO from Grants.gov. Never reuse a prior year's application without comparing it line by line against the new NOFO.
5. Not Contacting the Program Officer
The NOFO lists program contacts in Section G for a reason. Calling or emailing the program officer to discuss your project idea before writing is standard practice. You'll learn whether your approach fits the program's intent, whether similar projects have been funded before, and whether there are specific emphases the agency is prioritizing this cycle. This isn't insider information. It's publicly encouraged.
Where to Find NOFOs
Grants.gov
Grants.gov is the starting point for openly competed federal financial-assistance opportunities. Search by agency, eligibility, funding instrument, and keyword, then open the full current notice before treating a result as available.
Federal Register
Some agencies publish related notices in the Federal Register. Use the full current NOFO and its named agency contact to resolve any discrepancy or question about an application route.
Agency Websites
Individual agencies maintain their own lists:
- NIH: NIH Guide for Grants and Contracts
- NSF: NSF Funding Opportunities
- ED: Department of Education Forecast of Funding Opportunities
- SAMHSA: SAMHSA Grants
SAM.gov
SAM.gov also lists federal assistance opportunities. Its database includes both Grants.gov listings and some additional cooperative agreement and other assistance opportunities.
NOFO Timelines: What to Expect
Understanding typical NOFO timelines helps you plan your grant-seeking calendar.
Forecasting: A forecast is planning information, not an application route. Verify that a full current NOFO is available before committing proposal work.
Application window: The current NOFO controls dates and times. Section 200.204 generally calls for at least 60 calendar days of availability and no fewer than 30 absent exigent circumstances, but applicants must use the exact notice deadline.
Review and award timing: Do not use a generic calendar. The notice may state an anticipated award date, but review, award, and notification timing vary by program.
Feedback: Follow the current NOFO and agency process for any unsuccessful-applicant notification or debriefing information.
What to Do After You Find a NOFO
Finding a relevant NOFO is the starting line, not the finish. Here's a realistic prep timeline.
Day 1-3: Complete the five-pass reading process above. Determine go/no-go.
Day 3-7: Contact the program officer. Confirm your project concept fits. Ask about common mistakes from prior cycles.
Day 7-14: Build your team. Identify co-PIs, partners, evaluators, and consultants. Begin collecting letters of support and MOUs.
Day 14-45: Draft the narrative, following your scoring map. Build the budget simultaneously with the narrative so costs match activities described.
Day 45-55: Internal review. Have someone who wasn't involved in the writing review the draft against the NOFO requirements checklist.
Day 55-58: Finalize, format, and upload to Grants.gov Workspace.
Day 58-60: Submit at least 48 hours before the deadline. Grants.gov validation can take up to 48 hours, and if your submission is rejected for a technical error, you'll need time to fix and resubmit.
For the full submission walkthrough, see our Grants.gov application guide.
What the NOFO Doesn't Tell You: Turn It Into a Go-or-Skip Decision
The current NOFO is the authority for its award. What the official notice misses is whether your organization can prove its readiness before the deadline. Based on our review of source checks, Grantsights review records the gap between the required terms and the applicant's evidence: registrations, partner commitments, eligible project scope, budget capacity, and submission ownership.
For example, a nonprofit may appear eligible but still be a bad fit if its required partner has not committed, cost sharing cannot be documented, or the team cannot obtain the named registrations in time. The next action is to list the missing proof, ask the NOFO contact a specific question, and skip the opportunity if that proof cannot be obtained before submission.
| Check | Evidence | Decision rule |
|---|---|---|
| Live route | Current Grants.gov listing and full NOFO | Stop if the notice is closed, superseded, or lacks a usable application path. |
| Eligibility | Exact applicant, project, and cost-share language | Skip if any threshold cannot be documented. |
| Readiness | Registrations, partners, budget, and submission owner | Pause until each required item has an accountable owner. |
| Timing | Deadline, questions date, internal review, and upload plan | Skip if validation and correction time are unavailable. |
According to 2 CFR 200.204, the Grants.gov notice summary includes funding details, key dates, an executive summary, and agency contact information. According to Appendix I, the full NOFO must use the required sections. Those sources establish the opportunity. The source screen establishes whether to pursue it.
Related Application Checks
- How to apply through Grants.gov
- How to find and read a grant opportunity
- How to register on SAM.gov
- What a UEI is
- How cost sharing works
- Browse current grant routes
- Check the report catalog
FAQ: Common Questions
What is the difference between a NOFO and an RFP?
A NOFO announces a federal financial-assistance opportunity. An RFP commonly seeks offers for a procurement contract. Read the current solicitation and its governing terms because agency labels and submission rules vary.
Where can I find NOFOs for federal grants?
For openly competed federal financial assistance, start with Grants.gov and the full current notice. Section 200.204 requires specified summary information there and Appendix I information in the full NOFO. Use the named agency contact for questions that the notice does not answer.
How long do I have to respond to a NOFO?
Use the exact dates and times in the current NOFO. Section 200.204 generally calls for 60 calendar days of availability and no fewer than 30 absent exigent circumstances, but the notice controls the application schedule.
What does NOFO stand for in government grants?
NOFO stands for Notice of Funding Opportunity. It is the standardized federal term for the official announcement that a grant or cooperative agreement competition is open. OMB directed agencies to adopt NOFO as the uniform term through the 2024 revision of 2 CFR Part 200 (Uniform Guidance), replacing older terms like FOA, NOFA, RFA, and SGA that varied by agency. The goal was consistency so applicants could find similar information in the same format regardless of which agency issued the announcement.
Can I apply for a NOFO if I've never received a federal grant before?
Possibly. Read the current Eligibility section rather than assuming a general applicant type is enough. It states applicant and project restrictions, cost sharing, registration requirements, and disqualifying conditions.
Sources
- 2 CFR 200.204: Notices of Funding Opportunities
- 2 CFR Part 200, Appendix I: Full Text of Notice of Funding Opportunity
- OMB 2024 Uniform Guidance Revision (Federal Register)
- CDC: Understanding the Notice of Funding Opportunity
- NIFA: New Name, Same Opportunity: RFA is Now NOFO
- Grants.gov: Search Funding Opportunities
Route hubs
Move from this guide into the strongest grant route
Broad grant searches often split by sponsor, applicant type, location, or notice number. These hub pages help you choose the route before opening exact program records.
NIH grant routes
Compare R01, R03, R21, R35, K awards, fellowships, training, SBIR, STTR, and exact NIH program pages.
NSF grant routes
Compare CAREER, MRI, GRFP, EPSCoR, Noyce, STEM education, research, and NSF program pages.
SBIR Phase I
Use for small-business R&D searches that need agency fit, Phase I timing, and award-size checks.
Nonprofit grant routes
Move broad nonprofit searches into federal, state, foundation, local, and eligibility-screened paths.
Church grant routes
Route church and faith-site searches into repair, security, food, housing, disaster, and public-service paths.
State grant routes
Separate federal, state, city, county, nonprofit, education, and small-business searches by location.
Notice-number lookup
Use when a query names a PAR, RFA, FOA, HRSA, CDC, NSF, or Grants.gov opportunity number.
NOFO route chooser
Use the notice number, deadline, and review criteria first
NOFO searches often start with a definition, but the useful next step is deciding whether the notice is real, current, eligible, and worth writing for. Use these paths to move from the acronym into notice lookup, deadline planning, and award history.
Look up notice numbers
Use for PAR, RFA, HRSA, CDC, NSF, and Grants.gov opportunity numbers that already show search demand.
Plan the deadline
Turn close date, letters, registrations, forms, and internal reviews into a workback schedule.
Find grants that fit you
Free eligibility check: answer 12 questions and see ranked matches with deadlines and fit reasons.
Search federal programs
Move from the term definition into current federal opportunities, agencies, and deadlines.
Proposal workflow
Use when the NOFO has the right applicant type and the next task is organizing the proposal.
Check award history
Use USASpending data to see prior recipients, states, award sizes, and assistance-listing patterns.
NOFO versus FOA versus NOSI
NOFO
The current umbrella term for a federal notice that announces discretionary grant or cooperative agreement funding.
FOA
Older funding opportunity announcement wording. Some systems and agencies still show FOA language.
NOSI
An NIH notice of special interest. It signals agency interest but usually points applicants back to a related NOFO.
Read before writing
Eligibility section
Check applicant type, entity status, geography, cost share, and any prior-award or partnership rules first.
Dates and forms
Confirm forecast, synopsis, package, close date, required attachments, and version updates before drafting.
Review criteria
Map need, project design, budget, capacity, and outcomes to the scoring language in the notice.
Notice-number examples
PAR and PA
Common NIH announcement codes, often used for program announcements and parent paths.
RFA
Request for applications, often tied to a more focused agency priority or set-aside.
HRSA, CDC, NSF, USDA
Agency notices may use different number formats, but the notice still controls eligibility and submission rules.
Published by
GrantsightsGrantsights editorial content is reviewed against current program pages, award lists, notices, regulations, and application guidance before publication.
Source review
Each guide names the primary sources used for its program. Status, deadlines, eligibility, application routes, and award figures are checked against the source that owns that fact before publication. The page identifies its review date and separates current rules from historical planning evidence.
- Primary sources selected from the agency, notice, regulation, or award system that owns each claim
- Status, deadline, eligibility, and award figures rechecked at the page's displayed source-review date
Editorial accountability
Erik Jia, Founder and Editorial LeadAccountable for source standards, corrections, product claims, and data-source transparency.
Best follow-up
Use the notice number to find the exact program
After defining NOFO terms, move into source notice lookup, current deadlines, agency pages, and exact grant-program records.
Source-reviewed route check. No payment on this step.
Next steps
Where to go next on NOFO meaning
These next pages help you move from research into a specific grant choice.
Look up grant notice numbers
Open matching PAR, RFA, HRSA, CDC, NSF, and Grants.gov program pages.
Plan the deadline
Turn close date, registrations, forms, partner letters, and reviews into a workback plan.
High-demand program pages
Move from terminology into the grant pages already selected for search demand.
Find grants that fit you
Free eligibility check: answer 12 questions and see ranked matches with deadlines and fit reasons.
Search federal programs
Move from the acronym into current opportunities, agencies, and deadlines.
Check award history
Use USASpending data after the notice confirms the program family.
Source trust
How this guide is reviewed
Each guide is checked against the official notice, agency pages, and federal award records, and it's dated when those facts change.
Federal Program Records to Compare
Use these current program records to check eligibility, award history, deadlines, and past winners before your team commits writing time.
- National K12 Program for the Career Development of Clinician-Scientists in Diabetes Research (Diabetes-DOCS)HHS · closed
- Strategies to Improve Health Outcomes and Reduce Health Disparities in Rural Populations (R01 Clinical Trial Optional)HHS · closed
- Clinical Trials Addressing Unmet Needs of Rare Neurodegenerative Diseases (R01) Clinical Trials RequiredHHS · upcoming
- Ancillary Studies to Ongoing Clinical Projects (R21 Clinical Trial Not Allowed)HHS · closed
- Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R01 Clinical Trial Not Allowed)HHS · closing-soon
- Advancing Healthcare for Older Adults from Populations that Experience Health Disparities (R01 - Clinical Trial Optional)HHS · open
- Exploratory/Developmental Grants Related to the World Trade Center Health Program (R21)HHS · open
- NIH Research Project Grant (Parent R01 Clinical Trial Required)HHS · open
Show 40 more program recordsShow fewer program records
- Research Projects to Enhance Applicability of Mammalian Models for Translational Research (R01 Clinical Trial Not Allowed)HHS · closed
- Revision Applications for Validation of Biomarker Assays Developed Through NIH-Supported Research Grants (R01 Clinical Trial Not Allowed)HHS · closed
- Investigator Initiated Innovation in Computational Genomics and Data Science (R21 Clinical Trial Not Allowed)HHS · closed
- Research Grants in Clinical Informatics (R01 Clinical Trial Optional)HHS · open
- Screening and Functional Validation of Genomic Variants Associated with Human Congenital Anomalies (R01 Clinical Trial Not Allowed)HHS · open
- Development of Animal Models and Related Biological Materials for Research (R21 Clinical Trial Not Allowed)HHS · open
- Early-Stage Dissemination and Implementation Research in Communication Disorders (R21 Clinical Trial Optional)HHS · open
- NIH Research Educational Program - Mentoring Activities & Networks (Parent R25/UE5 - Clinical Trial Not Allowed)HHS · open
- NIH Director's New Innovator Award (DP2 Clinical Trial Optional)HHS · closed
- NIH Director's Early Independence Award (DP5 Clinical Trial Optional)HHS · closed
- NIH Research Education Program - Research Experiences (Parent R25 - Clinical Trial Not Allowed)HHS · open
- Biomedical Technology Optimization and Dissemination Center (BTOD) (RM1 - Clinical Trial Not Allowed)HHS · open
- Institutional Mentored Career Development Award (Parent K12) (Clinical Trials Not Allowed)HHS · open
- NIAID Clinical Trial Implementation Cooperative Agreement (U01 Clinical Trial Required)HHS · open
- 2026 National Unemployment Insurance Convening Reimbursement InstructionsDOL · closed
- Alumni Engagement Innovation Fund (AEIF) 2026: Exchange Alumni Advancing Freedom250DOS- · closed
- AnalysisNSF · closed
- ancient DNA for Modern Genomics (aDMG) Data Generation and Resource CenterHHS · upcoming
- Annual Program Statement for U.S. Presentation at International Architecture BiennalesDOS- · open
- Annual Program Statement for U.S. Presentation at International Art BiennalesDOS- · open
- Archaeometry (AMTRY)NSF · closing-soon
- Autism Centers of Excellence R01HHS · upcoming
- Bioengineering Research Grants (BRG) (R01 Clinical Trial Optional)HHS · open
- BJA FY25 Public Safety and Mental Health Initiative Training and Technical AssistanceUSDO · closed
- BRAIN Initiative: Integrative Team-Research BRAIN Circuits Program - iBCP (RM1 Clinical Trial Not Allowed)HHS · open
- Calendar Year 2022 Disaster Water GrantsUSDA · closed
- Cancer Research Education Grants Program - Courses for Skills Development (R25 Clinical Trial Not Allowed)HHS · closed
- Carcinogen Hazard Assessment Monographs Program (CHAMP) (R01 Clinical Trial Not Allowed)HHS · open
- Clinical Coordinating Center for Multi-Site Investigator-Initiated Clinical Trials (Collaborative UG3/UH3 Clinical Trial Required)HHS · open
- Clinical Studies of Orphan Products Addressing Unmet Needs of Rare Diseases (R01 Clinical Trials Required)HHS · upcoming
- COE for Technical Training and Human PerformanceDOT · closed
- Cognitive Neuroscience (CogNeuro)NSF · open
- Complex Integrated Multi-Component Projects in Aging Research (U19 Clinical Trial Optional)HHS · upcoming
- Consortia for Structure-based Immunogen Design for HIV (CSID-HIV)HHS · closed
- Cooperative Agreement to Support a Human Abuse Potential Study of Botanical Kratom (U01 Clinical Trial Required)HHS · upcoming
- Core Centers for Clinical Research (CCCR) (P30 Clinical Trial Not Allowed)HHS · closed
- Coupling, Energetics, and Dynamics of Atmospheric RegionsNSF · closed
- Critical Path Public Private Partnerships Clinical Trials OptionalHHS · upcoming
- Dental Primary Care Practice-Based Research Network: Clinical Trial or Observational Study Planning and Implementation Cooperative AgreementHHS · upcoming
- Development and Maintenance of Human and Animal Food Rapid Response Teams (U2F) Clinical Trials Not AllowedHHS · upcoming
Frequently Asked Questions
What is the difference between a NOFO and an RFP?
A NOFO (Notice of Funding Opportunity) announces federal grant or cooperative agreement funding, governed by 2 CFR Part 200. An RFP (Request for Proposals) typically solicits bids for a contract where the government purchases specific goods or services. NOFOs result in grants with programmatic flexibility. RFPs result in contracts with deliverable-based payment. Some agencies still use RFP loosely for grant competitions, but under federal regulations, the correct term for grant funding announcements is NOFO.
Where can I find NOFOs for federal grants?
For openly competed federal financial assistance, start with Grants.gov and the full notice. Under 2 CFR 200.204, agencies must display specified summary information there and must include Appendix I information in the full NOFO. Agency program pages can provide context, but the current notice controls eligibility, dates, and submission instructions.
How long do I have to respond to a NOFO?
Check the current NOFO for its exact dates and times. Under 2 CFR 200.204, agencies should make opportunities available for at least 60 calendar days and should not use less than 30 days unless exigent circumstances justify it, but each notice controls its own submission schedule.
What does NOFO stand for in government grants?
NOFO stands for Notice of Funding Opportunity. It is the standardized federal term for the official announcement that a grant or cooperative agreement competition is open. OMB directed agencies to adopt NOFO as the uniform term through the 2024 revision of 2 CFR Part 200 (Uniform Guidance), replacing older terms like FOA, NOFA, RFA, and SGA that varied by agency. The goal was consistency so applicants could find similar information in the same format regardless of which agency issued the announcement.
Can I apply for a NOFO if I've never received a federal grant before?
Possibly. Read the current Eligibility section rather than assuming a general applicant type is enough. The NOFO states applicant and project restrictions, cost sharing, registration requirements, and any disqualifying conditions.
Last updated: July 25, 2026. This page is reviewed regularly and updated when eligibility requirements, deadlines, or funding amounts change.
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Complete Guide
How to Write a Federal Grant Proposal (2026 Guide)
Federal grant proposals average 50-100 pages. This guide covers every section and scoring criteria for writing a proposal that reviewers score highly.
CalFresh 2026-27: Income Limits, Eligibility, Students, CFAP, and How to Apply on BenefitsCal
CalFresh is California's SNAP. From Oct 1, 2026 a family of 4 qualifies with up to $5,500 a month gross income and can get up to $1,023. How to apply.
Section 1332 Waiver Guide: Guardrails, Funding, and State Readiness
Section 1332 waiver guide for 2026: guardrails, pass-through funding, public notice, state readiness, and alternatives now.
How to Write a Grant Sustainability Plan (2026 Guide)
Grant sustainability plans need 3 to 5 specific revenue sources with dollar amounts. Learn the 5 strategies that score highest with federal reviewers.
Food Stamps in Florida 2026-27: Income Limits, Work Rules, and How to Apply Through ACCESS Florida
Florida food stamps (SNAP) through DCF: gross income up to 200% of poverty, $1,023 max for a family of 4, new work rules, interviews and EBT card help.
Food Stamps in Georgia 2026-27: Income Limits, Georgia Gateway, Work Rules and Your EBT Card
Georgia SNAP for Oct 2026 to Sept 2027: $3,575 gross limit for a family of 4, up to $1,023 a month. How to apply on Georgia Gateway, work rules and EBT.